Менопаузальная гормональная терапия > LOW-DOSE ESTRADIOL SPRAY TO TREAT VASOMOTOR SYMPTOMS

27 Апр 6900

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Low-Dose Estradiol Spray to Treat Vasomotor Symptoms https://journals.lww.com/greenjournal/pages/articleviewer.aspx?year=2008&issue=06000&article=00015&type=Fulltext

(Опыт применения препарата Лензетто)

A randomized, double-blind, placebo-controlled, multicenter, parallel-group clinical trial was conducted. Postmenopausal women (N=454) with at least eight moderate-to-severe hot flushes per day applied daily, one, two, or three E2 (90 microliter spray contains 1.53 mg E2) or matching placebo sprays. The primary efficacy endpoints were mean change from baseline in frequency and severity of moderate-to-severe hot flushes at weeks 4 and 12. https://journals.lww.com/greenjournal/pages/articleviewer.aspx?year=2008&issue=06000&article=00015&type=Fulltext